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Russian physiologist (1849–1936) best known for his investigation of conditioned reflex through the use of experiments involving salivating dogs. He was awarded the Nobel Prize in Medicine in 1904. ALS in German, signed “I. Pawlow,” one page both sides, 4.5 x 7, May 13, 1911. Handwritten letter to a friend, offering some advice on family and its effect on a scientist's productivity. In full (translated): "Dear friend, Permit me to call you so. My warmest congratulations on your engagement. Only marriage, a family of one’s own, makes a man’s life complete. I remember well how my capacity for work grew and deepened after marriage, in the circumstances of family life. It always seemed to me that my best work came at the same time as major family events (like the birth of children). I hope and fervently wish that your marriage will be the happiness and the energy of your life also. My wife and children remember well your stay in Petersburg and send you warm greetings." In fine condition, with a brief biographical notation penned at the bottom in another hand.
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