Medical scientist (1899–1978) who co-discovered insulin in 1921. ALS signed “Charles H. Best,” one page, 8.5 x 5.5, University of Toronto letterhead, September 21, 1954. Letter to William Wedge, in full: “Thank you for your very kind and thoughtful note.” In fine condition, with expected mailing folds (one fold passing through two letters of the signature) and a trimmed lower edge. Accompanied by the original mailing envelope. Pre-certified PSA/DNA.
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