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Founder of the science of phrenology (1776–1832). ALS signed 'J. Spurzheim, M.D.,' one page, 7.25 x 9, October 15, 1827. In part: 'Having lectured in Cambridge on the structure and functions of the brain, and I may say with great success, I beg your permission to deliver the same lectures at the university of Oxford.' Intersecting folds, areas of toning, and scattered spots of soiling, otherwise fine condition. RRAuction COA.