German physician and physicist, inventor of the opthalmoscope. Original vintage sepia 4.25 x 6.5 cabinet photo by Reichard & Lindner of Berlin, signed in the lower border in fountain pen, “H. v. Helmholtz.” In fine condition, with small “1881” stamp to lower right of image and a few light surface marks. COA John Reznikoff/PSA/DNA and R&R COA.