Physicians Charles H. (1865–1939) and William J. (1861–1939) worked together in the family’s medical practice, which eventually evolved into the famed Mayo Clinic in Rochester, Minnesota. Two ink signatures, “C. H. Mayo” and “W. J. Mayo” on individual off-white approximately 3.25 x 2.25 cards. A hint of subtle soiling, and faint spots of glue residue to William’s card (lightly touching “W”), otherwise fine condition. R&R COA.