Among the greatest minds in medicine in the 19th century. As a result of his hard work and determination, great strides were made in the fields of pathological and physiological medicine. ALS in German, signed “R. Virchow,” one page, 5 x 8, January 9, 1895. Letter to an associate. Staple hole and pencil notation to top left, horizontal fold near bottom and mounting remnants to reverse, otherwise fine condition. R&R COA.