French microbiologist and chemist who demonstrated the germ theory of disease and developed techniques of inoculation, most notably the first vaccine against rabies. ALS in French, one page, 4 x 2.5, October 4, 1888. Unsigned ALS written to a woman, on the front of his personal calling card, presenting her with a souvenir she previously requested. Accompanied by the original mailing envelope. In fine condition. R&R COA.